Mulder and Scully - The X-Files, always. This Zeigen was with me since I was 11 and no matter how many shows I Liebe now, this one and this couple will always be my number 1! :)
Right now it's not together YET, but since my number one couple is Goren and Eames from Criminal Intent, literally if they go one Mehr episode without getting together it will be Can't be together except in the fanfic world because the writers are axing them from the show.