Wow ...the games are completely dissimilar, so it's hard to make a comparison. Also, this is an opinion question, so it should probably be a pick. It's like asking "What's better? Eating, oder getting a paycheck?"
Connect four is a two-player game that takes about five Minuten to play. Scene it? is a party game that takes at least half an Stunde and requires a TV and DVD player (or online video game system). If Du like a big group experience - and can gather a big group of people fairly regularly - then Scene it? is better. If Du prefer a quick game and/or Du only have one person Du can play with, then Connect Four is better.