Wilson

"When did it start?" House asked with a strange look on his face. Wilson sighed and sat down at the table.
"Nothing has started. Sometimes we have lunch together on the weekend..."
"You are seeing her outside of work and knowing you, paying for both meals, something has started."
"Look, three weeks Vor I ran in to her at that old movie theater on fourth and we thought it would be silly to not sit together since we were both seeing the same movie..."
"And one thing led to another?" House asked with a bitterness to his voice.
"We're friends. Just leave it alone, House."
"You know that Du like...

Wilson: We're not Friends anymore, House. I'm not sure we ever were.

Harsh words, probably the first hurtful words caring and sensitive Wilson ever sagte to House.
Being the show's main character, we got to see Mehr of House's side of that conversation than Wilson's, Mehr what House was feeling and House's reaction to those words than what they meant to Wilson.
Hearing those words from your best friend must be devastating alright, but what about saying them? What about the feelings that led Wilson to speak them out loud?

I always find it funny the great ammount of House Fans who are completely confident...