Can Du guys recommend me good Anime with a main character that has a female voice actress?

Ami Koshimizu voices Ryuko, the main character, from Kill la Kill

Chivalry of a Failed Knight.
Stella Vermilion(pictured) is voiced Von Shizuka Ishigami.

Akame from Akame ga Kill! is voiced Von Amamiya Sora.

Mahou Tsukai Pretty Cure!

Mirai Asahina is voiced Von Rie Takahashi.

Romeo x Juliet comes to mind, and I really enjoyed it. Brina Palencia (the voice of Haruhi from Ouran and Ciel from Black Butler) does a spectacular job as Juliet.
Also, Gatchaman Crowds, Maria Holic, and Coppelion are all highly recommended ^^

The Devil May Cry Anime is awesome with the sort of main characters Penny, Lady, and Trish, even though I hate Penny Because she's annoying.

Ryoma Echizen from Prince of Tennis.
He was voiced Von Junko Minagawa :)

One piece. The main character is Luffy(boy) but his voice actor is a woman.