Seriously?! This is one of the most orignal plots i'd ever seen in anime. Du dont see many Anime with alchemy well like NONE. Most other plos in Anime are common like Ninjas, shinigami, vampires, werewolves, aliens, ghosts, and a ton more.
Technically its in the Manga currently, shouldn't be too long before it happens though, but Fairy Tail. 2 Timeskips were used and for no reason but to troll its audience oder for the 2nd one, to Bewegen the plot along.